PUBLIKATIONEN

2017

  1. Wollert, Kai C., Tibor Kempf, Evangelos Giannitsis, Thomas Bertsch, Siegmund L. Braun, Harald Maier, Manfred Reim, and Robert H. Christenson. „An automated assay for growth differentiation factor 15.“ The Journal of Applied Laboratory Medicine: An AACC Publication 1, no. 5 (2017): 510-521; Acknowledgements to Stefanie Gaupp
  2. Grimsey, Paul, Nicolas Frey, Garnet Bendig, Juergen Zitzler, Oliver Lorenz, Dusanka Kasapic, and Christian E. Zaugg. „Population pharmacokinetics of exogenous biotin and the relationship between biotin serum levels and in vitro immunoassay interference.“ International journal of Pharmacokinetics 0 (2017); Acknowledgements to Christine Chowanetz and Stefanie Gaupp

2016

  1. Zeisler, Harald, Elisa Llurba, Frederic Chantraine, Manu Vatish, Anne Cathrine Staff, Maria Sennström, Matts Olovsson et al. „Predictive value of the sFlt-1: PlGF ratio in women with suspected preeclampsia.“ New England Journal of Medicine 374, no. 1 (2016): 13-22; Acknowledgements to Monika Sonner for study-data Monitoring
  2. Mueller, Christian, Evangelos Giannitsis, Michael Christ, Jorge Ordóñez-Llanos, James McCord, Richard Body, Mauro Panteghini et al. „Multicenter evaluation of a 0-hour/1-hour algorithm in the diagnosis of myocardial infarction with high-sensitivity cardiac troponin T.“ Annals of emergency medicine 68, no. 1 (2016): 76-87; Acknowledgements to Christine Chowanetz and Andrea Schatten
  3. Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia. (2016) Ruther J, Hagström ÅK, Brandstetter B, Hofferberth J, Bruckmann A, Semmelmann F, Fink M, Lowack H, Laberer S, Niehuis O, Deutzmann R, Löfstedt C, Sterner R. Sci Rep. 6:34697. PMID: 27703264
  4. IKKα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator RIPK1. (2016) Koppe C, Verheugd P, Gautheron J, Reisinger F, Kreggenwinkel K, Roderburg C, Quagliata L, Terracciano L, Gassler N, Tolba RH, Boege Y, Weber A, Karin M, Luedde M, Neumann UP, Weiskirchen R, Tacke F, Vucur M, Trautwein C, Lüscher B, Preisinger C, Heikenwalder M, Luedde T. Hepathology 64(4). PMID: 27396433
  5. Cardioprotection and lifespan extension by the natural polyamine spermidine. (2016) Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Nat Med.1428-1438. PMID: 27841876
  6. The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations. (2016) Fuchs H, Sabrautzki S, Przemeck GK, Leuchtenberger S, Lorenz-Depiereux B, Becker L, Rathkolb B, Horsch M, Garrett L, Östereicher MA, Hans W, Abe K, Sagawa N, Rozman J, Vargas-Panesso IL, Sandholzer M, Lisse TS, Adler T, Aguilar-Pimentel JA, Calzada-Wack J, Ehrhard N, Elvert R, Gau C, Hölter SM, Micklich K, Moreth K, Prehn C, Puk O, Racz I, Stoeger C, Vernaleken A, Michel D, Diener S, Wieland T, Adamski J, Bekeredjian R, Busch DH, Favor J, Graw J, Klingenspor M, Lengger C, Maier H, Neff F, Ollert M, Stoeger T, Yildirim AÖ, Strom TM, Zimmer A, Wolf E, Wurst W, Klopstock T, Beckers J, Gailus-Durner V, Hrabé de Angelis M. G3 (Bethesda). 6(12):4035-4046. PMID: 27815347
  7. Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice. (2016) Wittmann A, Grimm MO, Scherthan H, Horsch M, Beckers J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Ford SJ, Burton NC, Razansky D, Trümbach D, Aichler M, Walch AK, Calzada-Wack J, Neff F, Wurst W, Hartmann T, Floss T. PLoS One. 11(10). PMID: 27788151
  8. Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. (2016) Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M; German Mouse Clinic Consortium., Hrabě de Angelis M, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Nat Commun. 7:11317. PMID: 27122098
  9. CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection. (2016) Côme C, Cvrljevic A, Khan MM, Treise I, Adler T, Aguilar-Pimentel JA, Au-Yeung B, Sittig E, Laajala TD, Chen Y, Oeder S, Calzada-Wack J, Horsch M, Aittokallio T, Busch DH, Ollert MW, Neff F, Beckers J, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Chen Z, Lahesmaa R, Westermarck J. PLoS One. 11(4). PMID: 27100879
  10. Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice. (2016) Kumar S, Rathkolb B, Kemter E, Sabrautzki S, Michel D, Adler T, Becker L, Beckers J, Busch DH, Garrett L, Hans W, Hölter SM, Horsch M, Klingenspor M, Klopstock T, Rácz I, Rozman J, Vargas Panesso IL, Vernaleken A, Zimmer A, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Wolf E, Aigner B. PLoS One. 11(3). PMID: 27003440
  11. Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice. (2016) Korner G, Scherer T, Adamsen D, Rebuffat A, Crabtree M, Rassi A, Scavelli R, Homma D, Ledermann B, Konrad D, Ichinose H, Wolfrum C, Horsch M, Rathkolb B, Klingenspor M, Beckers J, Wolf E, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Blau N, Rozman J, Thöny B. J Inherit Metab Dis. 39(2). PMID: 26830550
  12. Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia. (2016) Diener S, Bayer S, Sabrautzki S, Wieland T, Mentrup B, Przemeck GK, Rathkolb B, Graf E, Hans W, Fuchs H, Horsch M, Schwarzmayr T, Wolf E, Klopocki E, Jakob F, Strom TM, Hrabě de Angelis M, Lorenz-Depiereux B. Mamm Genome. 27(3-4). PMID: 26803617
  13. Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. (2016) Halama A, Horsch M, Kastenmüller G, Möller G, Kumar P, Prehn C, Laumen H, Hauner H, Hrabĕ de Angelis M, Beckers J, Suhre K, Adamski J. Arch Biochem Biophys. 93-107. PMID: 26408941

2015

  1. Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma. (2015) Berchtold S, Grünwald B, Krüger A, Reithmeier A, Hähl T, Cheng T, Feuchtinger A, Born D, Erkan M, Kleeff J, Esposito I. Cancer Lett.721-32. PMID: 25449434
  2. Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells. (2015) Schulz AM, Stutte S, Hogl S, Luckashenak N, Dudziak D, Leroy C1, Forné I, Imhof A, Müller SA, Brakebusch CH, Lichtenthaler SF, Brocker T. J Cell Biol. 9;211(3) PMID: 26553928.
  3. Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines. (2015) Horsch M, Aguilar-Pimentel JA, Bönisch C, Côme C, Kolster-Fog C, Jensen KT, Lund AH, Lee I, Grossman LI, Sinkler C, Hüttemann M, Bohn E, Fuchs H, Ollert M, Gailus-Durner V, de Angelis MH, Beckers J. PLoS One. 10(8). PMID: 26263558
  4. Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers. (2015) Deng T, Zhu ZI, Zhang S, Postnikov Y, Huang D, Horsch M, Furusawa T, Beckers J, Rozman J, Klingenspor M, Amarie O, Graw J, Rathkolb B, Wolf E, Adler T, Busch DH, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, van der Velde A, Tessarollo L, Ovcherenko I, Landsman D, Bustin M. Genome Res. 25(9):1295-308. PMID: 26156321
  5. Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels. (2015) Rathkolb B, Klempt M, Sabrautzki S, Michel D, Klaften M, Laufs J, Sedlmeier R, Hans W, Fuchs H, Muckenthaler MU, Horsch M, Campagna DR, Fleming M, Hrabé de Angelis M, Wolf E, Aigner B. Biometals. 28(2):293-306. PMID: 25636453
  6. Generation of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity. (2015) Keeney JG, O’Bleness MS, Anderson N, Davis JM, Arevalo N, Busquet N, Chick W, Rozman J, Hölter SM, Garrett L, Horsch M; German Mouse Clinic Consortium., Beckers J, Wurst W, Klingenspor M, Restrepo D, de Angelis MH, Sikela JM. Mamm Genome. 26(1-2):33-42. PMID: 25308000.

2014

  1. Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. (2014) Bulau AM, Nold MF, Li S, Nold-Petry CA, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello CA, Bufler P. Proc Natl Acad Sci U S A. 111(7). PMID: 24481253
  2. Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via crosstalk with hepatocytes. (2014) Wolf MJ, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, Ringelhan M, Simonavicius N, Egger M, Wohlleber D, Lorentzen A, Einer C, Schulz S, Clavel T, Protzer U, Thiele C, Zischka H, Moch H, Tschöp M, Tumanov AV, Haller D, Unger K, Karin M, Kopf M, Knolle P, Weber A, Heikenwalder M17. Cancer Cell. 26(4):549-64. PMID: 25314080
  3. Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation. (2014) Gewies A, Gorka O, Bergmann H, Pechloff K, Petermann F, Jeltsch KM, Rudelius M, Kriegsmann M, Weichert W, Horsch M, Beckers J, Wurst W, Heikenwalder M, Korn T, Heissmeyer V, Ruland J. Cell Rep. 9(4):1292-305. PMID: 25456129
  4. Uromodulin retention in thick ascending limb of Henle’s loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease. (2014) Horsch M, Beckers J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Aigner B, Kemter E. PLoS One. 9(11). PMID: 25409434
  5. MiR-34a deficiency accelerates medulloblastoma formation in vivo. Thor T, Künkele A, Pajtler KW, Wefers AK, Stephan H, Mestdagh P, Heukamp L, Hartmann W, Vandesompele J, Sadowski N, Becker L, Garrett L, Hölter SM, Horsch M, Calzada-Wack J, Klein-Rodewald T, Racz I, Zimmer A, Beckers J, Neff F, Klopstock T, De Antonellis P, Zollo M, Wurst W, Fuchs H, Gailus-Durner V, Schüller U, de Angelis MH, Eggert A, Schramm A, Schulte JH. Int J Cancer. 136(10):2293-303. PMID: 25348795
  6. Generation of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity. (2014) Keeney JG, O’Bleness MS, Anderson N, Davis JM, Arevalo N, Busquet N, Chick W, Rozman J, Hölter SM, Garrett L, Horsch M; German Mouse Clinic Consortium., Beckers J, Wurst W, Klingenspor M, Restrepo D, de Angelis MH, Sikela JM. Mamm Genome. 26(1-2):33-42. PMID: 25308000
  7. Peroxidasin is essential for eye development in the mouse. (2014) Yan X, Sabrautzki S, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Hrabě de Angelis M, Graw J. Hum Mol Genet. 23(21):5597-614. PMID: 24895407
  8. Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. (2014) Spieler D, Kaffe M, Knauf F, Bessa J, Tena JJ, Giesert F, Schormair B, Tilch E, Lee H, Horsch M, Czamara D, Karbalai N, von Toerne C, Waldenberger M, Gieger C, Lichtner P, Claussnitzer M, Naumann R, Müller-Myhsok B, Torres M, Garrett L, Rozman J, Klingenspor M, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Beckers J, Hölter SM, Meitinger T, Hauck SM, Laumen H, Wurst W, Casares F, Gómez-Skarmeta JL, Winkelmann J. Genome Res. 24(4):592-603. PMID: 24642863
  9. Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. (2014) Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R. J Immunol. 192(8):3507-17. PMID: 24639353
  10. Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. (2014) Stribl C, Samara A, Trümbach D, Peis R, Neumann M, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Beckers J, Horsch M, Neff F, Kremmer E, Koob S, Reichert AS, Hans W, Rozman J, Klingenspor M, Aichler M, Walch AK, Becker L, Klopstock T, Glasl L, Hölter SM, Wurst W, Floss T. J Biol Chem. 289(15):10769-84. PMID: 24515116

2013

  1. Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis. (2013) Kahle M, Horsch M, Fridrich B, Seelig A, Schultheiß J, Leonhardt J, Irmler M, Beckers J, Rathkolb B, Wolf E, Franke N, Gailus-Durner V, Fuchs H, de Angelis MH, Neschen S. Mol Metab. 2(4):435-46. PMID: 24327959
  2. Pitx3 directly regulates Foxe3 during early lens development. (2013) Ahmad N, Aslam M, Muenster D, Horsch M, Khan MA, Carlsson P, Beckers J, Graw J. Int J Dev Biol. 57(9-10):741-51. PMID: 24307298
  3. Prdm6 is essential for cardiovascular development in vivo. (2013) Gewies A, Castineiras-Vilarino M, Ferch U, Jährling N, Heinrich K, Hoeckendorf U, Przemeck GK, Munding M, Groß O, Schroeder T, Horsch M, Karran EL, Majid A, Antonowicz S, Beckers J, Hrabé de Angelis M, Dodt HU, Peschel C, Förster I, Dyer MJ, Ruland J. PLoS One. 8(11). PMID: 24278461
  4. Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice. (2013) Kemter E, Prückl P, Rathkolb B, Micklich K, Adler T, Becker L, Beckers J, Busch DH, Götz AA, Hans W, Horsch M, Ivandic B, Klingenspor M, Klopstock T, Rozman J, Schrewe A, Schulz H, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Wolf E, Aigner B. PLoS One. 8(10). PMID: 24205203
  5. Rapamycin extends murine lifespan but has limited effects on aging. (2013) Neff F, Flores-Dominguez D, Ryan DP, Horsch M, Schröder S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Garrett L, Hans W, Hettich MM, Holtmeier R, Hölter SM, Moreth K, Prehn C, Puk O, Rácz I, Rathkolb B, Rozman J, Naton B, Ordemann R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Ehninger G, Graw J, Höfler H, Klingenspor M, Klopstock T, Ollert M, Stypmann J, Wolf E, Wurst W, Zimmer A, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Ehninger D. J Clin Invest. 123(8):3272-91. PMID: 23863708
  6. High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner. (2013) Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Hölter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Garfinkel B, Orly J, Ovcharenko I, Bustin M. J Biol Chem. 288(23):16690-703. PMID: 23620591
  7. SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. (2013) Ju L, Wing J, Taylor E, Brandt R, Slijepcevic P, Horsch M, Rathkolb B, Rácz I, Becker L, Hans W, Adler T, Beckers J, Rozman J, Klingenspor M, Wolf E, Zimmer A, Klopstock T, Busch DH, Gailus-Durner V, Fuchs H, de Angelis MH, van der Horst G, Lehmann AR. DNA Repair (Amst). 12(5):356-66. PMID: 23518413

2012

  1. Fasciculation and guidance of spinal motor axons in the absence of FGFR2 signaling. (2012) Huettl RE, Haehl T, Huber AB. PLoS One. 7(7). PMID: 22815929
  2. Innovations in phenotyping of mouse models in the German Mouse Clinic. (2012) Fuchs H, Gailus-Durner V, Neschen S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Dewert A, Fridrich B, Garrett L, Glasl L, Götz A, Hans W, Hölter SM, Horsch M, Hurt A, Janas E, Janik D, Kahle M, Kistler M, Klein-Rodewald T, Lengger C, Ludwig T, Maier H, Marschall S, Micklich K, Möller G, Naton B, Prehn C, Puk O, Rácz I, Räss M, Rathkolb B, Rozman J, Scheerer M, Schiller E, Schrewe A, Steinkamp R, Stöger C, Sun M, Szymczak W, Treise I, Vargas Panesso IL, Vernaleken AM, Willershäuser M, Wolff-Muscate A, Zeh R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Eickelberg O, Favor J, Graw J, Höfler H, Höschen C, Katus H, Klingenspor M, Klopstock T, Neff F, Ollert M, Schulz H, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Hrabě de Angelis M. Mamm Genome. 23(9-10):611-22. PMID: 22926221
  3. Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms. (2012) Thiele F, Cohrs CM, Flor A, Lisse TS, Przemeck GK, Horsch M, Schrewe A, Gailus-Durner V, Ivandic B, Katus HA, Wurst W, Reisenberg C, Chaney H, Fuchs H, Hans W, Beckers J, Marini JC, Hrabé de Angelis M. Hum Mol Genet. 21(16):3535-45. PMID: 22589248

2011

  1. In vivo expression of interleukin-37 reduces local and systemic inflammation in concanavalin A-induced hepatitis. (2011) Bulau AM, Fink M, Maucksch C, Kappler R, Mayr D, Wagner K, Bufler P. ScientificWorldJournal. 11:2480-90. PMID: 22235179
  2. Chronic liver inflammation and hepatocellular carcinoma: persistence matters. (2011) Weber A1, Boege Y, Reisinger F, Heikenwälder M. Swiss Med Wkly.141. PMID: 21557112
  3. Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS. (2011) Dann A, Poeck H, Croxford AL, Gaupp S, Kierdorf K, Knust M, Pfeifer D, Maihoefer C, Endres S, Kalinke U, Meuth SG, Wiendl H, Knobeloch KP, Akira S, Waisman A, Hartmann G, Prinz M., Nat Neurosci.15(1):98-106.
  4. On the occurrence of hypomyelination in a transgenic mouse model: a consequence of the myelin basic protein promoter? (2011) Gaupp S, Arezzo J, Dutta DJ, John GR, Raine CS. J Neuropathol Exp Neurol. 70(12):1138-50
  5. Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part II: gene regulation. (2011) Kobolak J, Horsch M, Geissler S, Mamo S, Beckers J, Dinnyes A. Cell Reprogram. 14(1):68-78.PMID: 22204593
  6. Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. (2011) Horsch M, Seeburg PH, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Garrett L, Götz A, Hans W, Higuchi M, Hölter SM, Naton B, Prehn C, Puk O, Rácz I, Rathkolb B, Rozman J, Schrewe A, Adamski J, Busch DH, Esposito I, Graw J, Ivandic B, Klingenspor M, Klopstock T, Mempel M, Ollert M, Schulz H, Wolf E, Wurst W, Zimmer A, Gailus-Durner V, Fuchs H, de Angelis MH, Beckers J. J Biol Chem. 286(21):18614-22. PMID: 21467037
  7. Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. (2011) Saarikangas J, Mattila PK, Varjosalo M, Bovellan M, Hakanen J, Calzada-Wack J, Tost M, Jennen L, Rathkolb B, Hans W, Horsch M, Hyvönen ME, Perälä N, Fuchs H, Gailus-Durner V, Esposito I, Wolf E, de Angelis MH, Frilander MJ, Savilahti H, Sariola H, Sainio K, Lehtonen S, Taipale J, Salminen M, Lappalainen P. J Cell Sci. 124(Pt 8):1245-55. PMID: 21406566
  8. Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. (2011) Lückerath K, Kirkin V, Melzer IM, Thalheimer FB, Siele D, Milani W, Adler T, Aguilar-Pimentel A, Horsch M, Michel G, Beckers J, Busch DH, Ollert M, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Staal FJ, Rajalingam K, Hueber AO, Strobl LJ, Zimber-Strobl U, Zörnig M. Blood. 117(2):519-29. PMID: 20971954
  9. Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. (2011) Niederfellner G, Lammens A, Mundigl O, Georges GJ, Schaefer W, Schwaiger M, Franke A, Wiechmann K, Jenewein S, Slootstra JW, Timmerman P, Brännström A, Lindstrom F, Mössner E, Umana P, Hopfner KP, Klein C.Blood. 118(2):358-67. PMID: 21444918
  10. Antibodies against CD20 or B-cell receptor induce similar transcription patterns in human lymphoma cell lines. (2011) Franke A, Niederfellner GJ, Klein C, Burtscher H. PLoS One. 6(2). PMID:21364752

2010

  1. TAK1 suppresses a NEMO‐dependent but NF‐kappaB‐independent pathway to liver cancer. (2010) Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T. Cancer Cell. 17(5):481-96. PMID: 20478530
  2. Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. (2010) Lückerath K, Kirkin V, Melzer IM, Thalheimer FB, Siele D, Milani W, Adler T, Aguilar-Pimentel A, Horsch M, Michel G, Beckers J, Busch DH, Ollert M, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Staal FJ, Rajalingam K, Hueber AO, Strobl LJ, Zimber-Strobl U, Zörnig M. Blood. 117(2):519-29. PMID: 20971954
  3. Mouse phenotyping. (2010) Fuchs H, Gailus-Durner V, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Da Silva-Buttkus P, Neff F, Götz A, Hans W, Hölter SM, Horsch M, Kastenmüller G, Kemter E, Lengger C, Maier H, Matloka M, Möller G, Naton B, Prehn C, Puk O, Rácz I, Rathkolb B, Römisch-Margl W, Rozman J, Wang-Sattler R, Schrewe A, Stöger C, Tost M, Adamski J, Aigner B, Beckers J, Behrendt H, Busch DH, Esposito I, Graw J, Illig T, Ivandic B, Klingenspor M, Klopstock T, Kremmer E, Mempel M, Neschen S, Ollert M, Schulz H, Suhre K, Wolf E, Wurst W, Zimmer A, Hrabě de Angelis M. Methods. 53(2):120-35. PMID: 20708688
  4. Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. (2010) Tocchetti A, Soppo CB, Zani F, Bianchi F, Gagliani MC, Pozzi B, Rozman J, Elvert R, Ehrhardt N, Rathkolb B, Moerth C, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Klingenspor M, Wolf E, Hrabé de Angelis M, Scanziani E, Tacchetti C, Scita G, Di Fiore PP, Offenhäuser N. PLoS One. 5(3). PMID: 20209148
  5. Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 (416insG ) mice. (2010) Rosemann M, Ivashkevich A, Favor J, Dalke C, Hölter SM, Becker L, Rácz I, Bolle I, Klempt M, Rathkolb B, Kalaydjiev S, Adler T, Aguilar A, Hans W, Horsch M, Rozman J, Calzada-Wack J, Kunder S, Naton B, Gailus-Durner V, Fuchs H, Schulz H, Beckers J, Busch DH, Burbach JP, Smidt MP, Quintanilla-Martinez L, Esposito I, Klopstock T, Klingenspor M, Ollert M, Wolf E, Wurst W, Zimmer A, de Angelis MH, Atkinson M, Heinzmann U, Graw J. Mamm Genome. 21(1-2):13-27. PMID: 20033184

2009

  1. Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system. (2009) Stegbauer J, Lee DH, Seubert S, Ellrichmann G, Manzel A, Kvakan H, Muller DN, Gaupp S, Rump LC, Gold R, Linker RA. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14942-7.
  2. Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice. (2009) Rosemann M, Ivashkevich A, Favor J, Dalke C, Hölter SM, Becker L, Rácz I, Bolle I, Klempt M, Rathkolb B, Kalaydjiev S, Adler T, Aguilar A, Hans W, Horsch M, Rozman J, Calzada-Wack J, Kunder S, Naton B, Gailus-Durner V, Fuchs H, Schulz H, Beckers J, Busch DH, Burbach JP, Smidt MP, Quintanilla-Martinez L, Esposito I, Klopstock T, Klingenspor M, Ollert M, Wolf E, Wurst W, Zimmer A, de Angelis MH, Atkinson M, Heinzmann U, Graw J. Mamm Genome. 2010 Feb;21(1-2):13-27. PMID: 20033184
  3. Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. (2009) Bach C, Gilch S, Rost R, Greenwood AD, Horsch M, Hajj GN, Brodesser S, Facius A, Schädler S, Sandhoff K, Beckers J, Leib-Mösch C, Schätzl HM, Vorberg I. J Biol Chem. 2009 Nov 6;284(45):31260-9. PMID: 19748890
  4. Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. (2009) Rubio-Aliaga I, Przemeck GK, Fuchs H, Gailus-Durner V, Adler T, Hans W, Horsch M, Rathkolb B, Rozman J, Schrewe A, Wagner S, Hoelter SM, Becker L, Klopstock T, Wurst W, Wolf E, Klingenspor M, Ivandic BT, Busch DH, Beckers J, Hrabé de Angelis M. PLoS One. 2009 Jun 29;4(6):e6054. PMID: 19562077
  5. Systemic first-line phenotyping. (2009) Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Mörth C, Mossbrugger I, Naton B, Prehn C, Puk O, Rathkolb B, Rozman J, Schrewe A, Thiele F, Adamski J, Aigner B, Behrendt H, Busch DH, Favor J, Graw J, Heldmaier G, Ivandic B, Katus H, Klingenspor M, Klopstock T, Kremmer E, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, de Angelis MH. Methods Mol Biol. 2009;530:463-509. PMID: 19266331
  6. The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. (2009) Fuchs H, Gailus-Durner V, Adler T, Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Mossbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M. Curr Pharm Biotechnol. 2009 Feb;10(2):236-43. PMID: 19199957
  7. Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study. (2009) Horsch M, Recktenwald CV, Schädler S, Hrabé de Angelis M, Seliger B, Beckers J. Br J Cancer. 2009 Feb 24;100(4):656-62. PMID: 19190631

2008

  1. Amelioration of experimental autoimmune encephalomyelitis in IL-4Ralpha-/- mice implicates compensatory up-regulation of Th2-type cytokines. (2008) Gaupp S, Cannella B, Raine CS. Am J Pathol. 2008 Jul;173(1):119-29.
  2. Pleiotropic effects in Eya3 knockout mice. (2008) Söker T, Dalke C, Puk O, Floss T, Becker L, Bolle I, Favor J, Hans W, Hölter SM, Horsch M, Kallnik M, Kling E, Moerth C, Schrewe A, Stigloher C, Topp S, Gailus-Durner V, Naton B, Beckers J, Fuchs H, Ivandic B, Klopstock T, Schulz H, Wolf E, Wurst W, Bally-Cuif L, de Angelis MH, Graw J. BMC Dev Biol. 2008 Dec 22;8:118. doi: 10.1186/1471-213X-8-118. PMID: 19102749
  3. Sighted C3H“ mice–a tool for analysing the influence of vision on mouse behaviour? (2008) Hoelter SM, Dalke C, Kallnik M, Becker L, Horsch M, Schrewe A, Favor J, Klopstock T, Beckers J, Ivandic B, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Graw J, Wurst W. Front Biosci. 2008 May 1;13:5810-23. PMID: 18508624
  4. Novel allele of crybb2 in the mouse and its expression in the brain. (2008) Ganguly K, Favor J, Neuhäuser-Klaus A, Sandulache R, Puk O, Beckers J, Horsch M, Schädler S, Vogt Weisenhorn D, Wurst W, Graw J. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1533-41. PMID: 18385073
  5. Systematic gene expression profiling of mouse model series reveals coexpressed genes. (2008) Horsch M, Schädler S, Gailus-Durner V, Fuchs H, Meyer H, de Angelis MH, Beckers J. Proteomics. 2008 Mar;8(6):1248-56. PMID: 18338826.
  6. Health effects of ambient particulate matter–biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures. (2008) Maier KL, Alessandrini F, Beck-Speier I, Hofer TP, Diabaté S, Bitterle E, Stöger T, Jakob T, Behrendt H, Horsch M, Beckers J, Ziesenis A, Hültner L, Frankenberger M, Krauss-Etschmann S, Schulz H. Inhal Toxicol. 2008 Feb;20(3):319-37. PMID: 18300050
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